• PURECIUM

    PURE BY NATURE

    Embodies the essence of pure, high-quality dietary supplement ingredients

  • ALPHA GPC(Alpha-Glycerophosphocholine)

    Boost Brain Power, Enhance Focus

    Alpha GPC 50%, 98%

    ALPHA GPC(Alpha-Glycerophosphocholine)

    Alpha GPC, a natural choline compound, fuels acetylcholine production—key for memory and focus. It crosses the blood-brain barrier easily, supporting cognitive function, mental clarity, and nerve health. Ideal for students, professionals, or anyone seeking sharpened focus, it’s a top choice in nootropic supplements for brain performance.

    Product name: ALPHA GPC(Alpha-Glycerophosphocholine)

    Molecular formula: C₈H₂₀NO₆P

    Starting material: (R)-(-)-3-Chloro-1,2-propanediol/Soybean

    Grade: Food

    Heavy Metals: USP/EP

    Pesticide residue: USP/EP

    Packing size: 25kg/drum

    Carrier:

    • Alpha GPC 50% DCP(Dibasic calcium phosphate)
    • Alpha GPC 50% Maltodextrin(Water soluble)

    CAS#: 28319-77-9

    Molecular weight:257.22 g/mol

    Source: Synthetic/Natural

    Specification: 50%/85%/98% Titrition

    Country of origin: China

    Residual solvent: USP/EP

    Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irridiation

    ISO, Kosher, halal, food safety certification

    Alpha GPC can be produced via two main routes: synthetic synthesis and extraction from soy sources, each with distinct processes.​

    The synthetic route typically starts with choline chloride and glycerophosphoric acid. Choline chloride undergoes esterification with glycerophosphoric acid under controlled temperature and pH, forming a phosphorylcholine intermediate. This is followed by stereoselective purification to isolate the L-α isomer (Alpha GPC), using chiral chromatography to ensure high enantiomeric purity. The process prioritizes efficiency, yielding high-purity Alpha GPC suitable for pharmaceutical and supplement use, with scalability for large-scale production.​

    Soy-derived Alpha GPC begins with soy lecithin, a natural source rich in phosphatidylcholine. The lecithin is first hydrolyzed using enzymes (e.g., phospholipases) or mild acids to break down phospholipid bonds, releasing glycerophosphorylcholine (GPC) mixtures. Further purification via solvent extraction or membrane filtration separates Alpha GPC from other lipids and impurities. This method leverages natural sources, appealing to consumers seeking plant-derived ingredients, though it requires careful processing to maintain bioactivity and achieve comparable purity to synthetic versions. Both processes ensure Alpha GPC meets quality standards for cognitive health applications.

    50% Alpha GPC powder, 98% Alpha GPC powder, and 85% Alpha GPC liquid differ significantly in purity, form, and applications.​

    98% Alpha GPC powder, with the highest purity, is favored in pharmaceutical formulations and high-potency supplements. Its concentrated form allows precise dosing, often used in nootropics targeting cognitive enhancement, such as memory support or focus-boosting products. It mixes well with other powdered ingredients, ideal for custom supplement blends, and suits users needing maximal Alpha GPC per serving.​

    50% Alpha GPC powder, diluted with carriers like maltodextrin, is more cost-effective. It’s commonly used in general wellness supplements, functional foods, or powdered drink mixes. The lower concentration makes it easier to incorporate into bulk formulations without altering texture, appealing to manufacturers balancing efficacy and affordability. It’s suitable for daily cognitive maintenance rather than high-dose therapeutic use.​

    85% Alpha GPC liquid, dissolved in water or glycerin, offers rapid absorption, making it ideal for fast-acting supplements. It’s often used in liquid tinctures, syrups, or ready-to-drink beverages, convenient for users who prefer liquid doses or have difficulty swallowing pills. Its liquidity also aids in uniform mixing in liquid products, though it requires careful storage to prevent degradation, unlike powder forms which are more shelf-stable.

    Alpha GPC is a key choline source, primarily supporting cognitive function by boosting acetylcholine, a neurotransmitter critical for memory and focus. It enhances learning capacity and mental clarity, making it valuable for students, professionals, and older adults.​

    It crosses the blood-brain barrier efficiently, aiding nerve cell communication and potentially slowing age-related cognitive decline. Studies link it to improved attention span and recall, especially in tasks requiring sustained focus.​

    Additionally, Alpha GPC supports neurological health, may enhance physical performance by aiding muscle control, and is used in supplements targeting brain health, nootropics, and post-stroke recovery to promote neural repair. Its multifaceted role makes it a versatile ingredient in cognitive and wellness formulations.

  • Alpha GPC
    Alpha GPC
    Alpha GPC
    Alpha GPC
    Alpha GPC
    Alpha GPC

  • ALPHA GPC(Alpha-Glycerophosphocholine) Frequently Asked Questions (FAQ)

    1. What does ALPHA GPC(Alpha-Glycerophosphocholine) look like?

    ALPHA GPC(Alpha-Glycerophosphocholine) 50%&98% is a fine white powder. 85% ALPHA GPC(Alpha-Glycerophosphocholine) is a liquid form.

    2. Do you sell finished ALPHA GPC(Alpha-Glycerophosphocholine) products?

    We do not sell finished products. We only supply raw ingredients. However, we can partner with a contract manufacturer to provide white-label services, including tablets, hard capsules, soft capsules, gummies, and more.

    3. Do you sell ALPHA GPC(Alpha-Glycerophosphocholine) to individual customers?

    Unfortunately, we do not sell our products to individual customers. Our target clientele includes distributors, contract manufacturers, and end-brand users.

    4. What is the MOQ and price for your ALPHA GPC(Alpha-Glycerophosphocholine)?

    Our MOQ is 25 kg. For detailed pricing, please contact our sales team at info@purecium.com.

    5. How can I purchase your ALPHA GPC(Alpha-Glycerophosphocholine)?

    For customers in the United States, Canada, and Mexico, pickup is available from our U.S. warehouse. We can also arrange for door-to-door delivery in these regions. For all other regions, orders will be shipped from China.

    6. What is the delivery time?

    Pickup from our U.S. warehouse is available within 2 days after the order is placed. Shipments from China are delivered within one week of the order being placed.

    7. What are the main forms of finished ALPHA GPC(Alpha-Glycerophosphocholine) products?

    Common forms include tablets, hard capsules, gummies, and sports drinks.

    8. Is ALPHA GPC(Alpha-Glycerophosphocholine) safe?

    Yes, the ALPHA GPC(Alpha-Glycerophosphocholine) we sell is food-grade. It is recognized as GRAS (Generally Recognized as Safe) by the FDA.

    9. What certifications can you provide for your ALPHA GPC(Alpha-Glycerophosphocholine)?

    We can provide the following certifications: ISO9001, Kosher, Halal, and FSSC22000.

    10. What's the packing size of ALPHA GPC(Alpha-Glycerophosphocholine)?

    Packing size: 25kg/drum.

    Drum size: 40cm*40cm*50cm.

    Net/Gross weight: 25/28 kg.

    11. What are the storage conditions and shelf life for ALPHA GPC(Alpha-Glycerophosphocholine)?

    Please store it in a tightly sealed, dry place, away from light. The shelf life is 24 months.

    12. Can you provide a stability report for ALPHA GPC(Alpha-Glycerophosphocholine)?

    Yes, we can provide data from both accelerated and long-term stability tests. Please contact our sales team at info@purecium.com to obtain the reports.

    13. Is the supply of ALPHA GPC(Alpha-Glycerophosphocholine) stable? What is your production capacity?

    Yes, we can ensure a consistent, long-term supply. Synthetic ALPHA GPC(Alpha-Glycerophosphocholine) has a designed capacity of 200 MT/year


    14. What is the mesh size of your ALPHA GPC(Alpha-Glycerophosphocholine)?

    Standard ALPHA GPC(Alpha-Glycerophosphocholine) is an 80 mesh powder.

    15. What are the sources of Alpha-GPC (Alpha-Glycerophosphocholine)?

    There are two sources: natural extraction and chemical synthesis.

    16. For the same specifications of Alpha-GPC, what is the price difference between the natural and synthetic sources?

    The natural source is more expensive, priced at approximately twice that of the synthetic source.

    17. What are the starting materials for these two sources of Alpha-GPC?

    The starting material for the natural source is soybean. The starting materials for the synthetic source are (R)-(-)-3-chloro-1,2-propanediol (CPD) and phosphorylcholine.

    18. Is the soybean used for the natural source non-GMO?

    Yes, it is non-GMO soybean.

    19. What are the other components of the two types of 50% Alpha-GPC?

    For the 50% Alpha GPC, the other 50% consists of excipients. The first type uses maltodextrin as the excipient. The second type uses Dihydrogen Calcium Phosphate (DCP, 49%) and Silicon Dioxide (1%).

    20. What are the other components of the 85% liquid Alpha-GPC?

    The other 15% is water.

    21. What are the differences in properties between the two types of 50% Alpha-GPC ?

    The standard one uses DCP and Silicon Dioxide as excipients. If water solubility is required, maltodextrin is typically used as the excipient.

    22.What is the difference in application between the 50% and 85% of Alpha-GPC?

    Alpha GPC 50% is primarily used as a raw material for dietary supplements. The 85% liquid is mainly used for cosmetics.

  • INQUIRY FORM

    Let's Discuss Your Needs

    Cookie Use
    We use cookies to ensure a smooth browsing experience. By continuing we assume you accept the use of cookies.
    Learn More