• PURECIUM

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    Embodies the essence of pure, high-quality dietary supplement ingredients

  • GINKGO BILOBA EXTRACT

    Natural Brain Function Enhancer

    Berberine hcl

    Ginkgo Biloba Extract

    Ginkgo Biloba Extract, derived from the ancient Ginkgo tree, is a natural supplement renowned for supporting cognitive health and circulation. Rich in antioxidants, it helps protect brain cells from oxidative stress, potentially enhancing memory, focus, and mental clarity. Widely used for centuries in traditional medicine, this herbal extract promotes blood flow, supports cardiovascular health, and may alleviate symptoms of cognitive decline, making it a popular choice for overall brain wellness.

    Product name: Ginkgo Biloba Extract

    Molecular formula: NA

    Starting material: Ginkgo biloba L

    Grade: Food grade

    Heavy Metals: USP/EP

    Pesticide residue: USP/EP

    Packing size: 25kg/drum

    CAS#: 90045-36-6

    Molecular weight: NA

    Source: Natural

    Specification: 24%/6%/5ppm

    Country of origin: China

    Residual solvent: USP/EP

    Allergen-free/Gluten-free/Non-GMO/Vegan/Non-Irridiation

    ISO, Kosher, halal, food safety certification

    Ginkgo biloba, one of the oldest living tree species, has a rich history of use spanning over 2,000 years. Originating in China, its leaves and seeds have been integral to Traditional Chinese Medicine (TCM) since ancient times. As early as the 11th century, ginkgo was documented in Chinese medical texts for treating respiratory issues, cognitive decline, and circulatory problems. By the 14th century, its use spread to other parts of Asia, including Japan and Korea, where it was valued for enhancing memory and vitality. In the 18th century, ginkgo caught the attention of European botanists, and by the 20th century, standardized ginkgo leaf extracts were developed in Germany, leading to its global popularity as a dietary supplement for cognitive and cardiovascular health.

    Today, ginkgo biloba is cultivated in several regions worldwide, with China remaining the largest producer, particularly in provinces like Jiangsu, Shandong, and Zhejiang. These areas benefit from fertile soils and a temperate climate ideal for ginkgo growth. South Korea and Japan also contribute significantly, with plantations focused on high-quality leaf production for extracts. In Europe, France and Germany host smaller but advanced cultivation sites, emphasizing standardized extracts for pharmaceutical use. The United States, particularly South Carolina, has emerged as a notable producer, leveraging modern agricultural techniques. Ginkgo trees thrive in well-drained soils and temperate climates, making these regions ideal. The global demand for ginkgo biloba extract, driven by its reputed benefits for memory and circulation, continues to fuel cultivation, with China accounting for over 60% of the world’s supply.

    ​Ginkgo biloba extract, derived from the leaves of the ancient Ginkgo tree, is celebrated for its potential health benefits, particularly in supporting cognitive and cardiovascular function. Rich in flavonoids and terpenoids, it acts as a potent antioxidant, protecting brain cells from oxidative stress and inflammation, which may enhance memory, focus, and mental clarity. Studies suggest it can improve cognitive performance in healthy individuals and slow cognitive decline in those with mild dementia or Alzheimer’s disease. By promoting blood circulation, ginkgo extract supports cardiovascular health, potentially reducing symptoms of peripheral artery disease and improving overall vascular function. It may also alleviate symptoms of anxiety and depression by modulating neurotransmitter activity. Additionally, ginkgo is used to relieve symptoms of premenstrual syndrome (PMS) and age-related macular degeneration due to its anti-inflammatory properties. Some evidence indicates it could help with tinnitus and vertigo by improving blood flow to the inner ear. While generally safe, its efficacy varies among individuals, and consultation with a healthcare provider is advised before use, especially for those on medications like blood thinners. Ginkgo biloba extract remains a popular natural supplement for brain health and vitality.

    ​

    The Chinese Pharmacopoeia (ChP), United States Pharmacopeia (USP36), and European Pharmacopoeia (EP8.0) outline distinct standards for Ginkgo biloba extract, reflecting regional regulatory and analytical priorities. The ChP, emphasizing traditional Chinese medicine, specifies a broader range of active components, including flavonoids (24–27%) and terpene lactones (6–12%), with detailed tests for bilobalide and ginkgolides A, B, and C. It uniquely requires testing for ginkgolic acids (a potential allergen) at a stringent limit of ≤10 ppm, reflecting safety concerns. The ChP also includes macroscopic and microscopic identification to ensure plant authenticity, aligning with its focus on herbal medicine.

    The USP36 prioritizes standardized extracts for dietary supplements, requiring 24–27% flavonoids and 5.4–12% terpene lactones, but it allows slightly higher ginkgolic acid levels (≤5 ppm). Its testing methods emphasize high-performance liquid chromatography (HPLC) for precise quantification, with less focus on traditional identification compared to the ChP. The USP also includes specific impurity tests, such as for rutin and quercetin, to ensure extract purity.

    The EP8.0, used across Europe, aligns closely with the USP but sets stricter limits for ginkgolic acids (≤5 ppm) and requires a more comprehensive impurity profile, including heavy metals and residual solvents. It employs similar HPLC methods but mandates additional validation for consistency across member states. The EP also emphasizes standardized extraction processes to ensure reproducibility.

    While all three pharmacopoeias aim to ensure safety and efficacy, the ChP integrates traditional practices, the USP focuses on

    supplement standardization, and the EP emphasizes regulatory harmonization and stringent impurity controls.

  • Ginkgo biloba extract
    Ginkgo biloba extract
    Ginkgo biloba extract
    Ginkgo biloba extract
    Ginkgo biloba extract
    Ginkgo biloba extract

  • Ginkgo Biloba Extract Frequently Asked Questions (FAQ)

    1. What does Ginkgo biloba extract look like?

    It is a brownish-yellow powder.

    2. Do you sell finished Ginkgo biloba extract products?

    We do not sell finished products. We only supply raw ingredients. However, we can partner with a contract manufacturer to provide white-label services, including tablets, hard capsules, soft capsules, and gummies.

    3. Do you sell Ginkgo biloba extract to individual customers?

    Unfortunately, we do not sell our products to individual customers. Our target clientele includes distributors, contract manufacturers, and end-brand users.

    4. What is the MOQ and price for your Ginkgo biloba extract?

    Our MOQ is 25 kg. For detailed pricing, please contact our sales team at info@purecium.com.

    5. How can I purchase your Ginkgo biloba extract?

    For customers in the United States, Canada, and Mexico, pickup is available from our U.S. warehouse. We can also arrange for door-to-door delivery in these regions. For all other regions, orders will be shipped from China.

    6. What is the delivery time?

    Pickup from our U.S. warehouse is available within 2 days after the order is placed. Shipments from China are delivered within one week of the order being placed.

    7. What are the main forms of finished Ginkgo biloba extract products?

    Common forms include tablets, hard capsules or softgel.

    8. What certifications can you provide for your Ginkgo biloba extract?

    We can provide the following certifications: ISO9001, Kosher, Halal, and FSSC22000.

    9. What's the packing size of Ginkgo biloba extract?

    Packing size: 25kg/drum.

    Drum size: 40cm*40cm*50cm.

    Net/Gross weight: 25/28 kg.

    10. What are the storage conditions and shelf life for Ginkgo biloba extract?

    Please store it in a tightly sealed, dry place, away from light. The shelf life is 24 months.

    11. Can you provide a stability report for Ginkgo biloba extract?

    Yes, we can provide data from both accelerated and long-term stability tests. Please contact our sales team at info@purecium.com to obtain the reports.

    12. Is the supply of Ginkgo biloba extract stable? What is your production capacity?

    Yes, we can ensure a consistent, long-term supply. It has a designed capacity of 300 MT/year.

    13. What is the mesh size of your Ginkgo biloba extract?

    Standard Ginkgo biloba extract is an 80-mesh powder.

    14. Does Ginkgo Biloba Extract Really Work? Is It Safe?
    The inclusion of Ginkgo biloba extract in pharmacopoeias of multiple countries and regions indicates its widely recognized effects globally. In the United States, Ginkgo biloba extract is classified as an ODI, compiled shortly after the passage of the Dietary Supplement Health and Education Act of 1994 (DSHEA). In Europe, Ginkgo biloba extract is considered a Novel Food, not subject to pre-market authorization under Regulation (EU) 2015/2283.

    15. Is There a Tree Age Requirement for Ginkgo Leaves Used in Extraction?
    There is a requirement for the age of Ginkgo leaves used in extraction, typically from trees aged 1–5 years. The content of flavonoids in Ginkgo leaves is related to tree age, with active components, especially flavonoids, significantly decreasing as tree age increases. The total flavonoid glycoside content in 1-year-old Ginkgo is significantly higher than in 4- or 7-year-old trees, with notable differences in quercetin content. Key structural genes in the flavonoid biosynthesis pathway are gradually downregulated with age, partly explaining the decrease in flavonoid content as trees age.

    16. In Which Season Are Ginkgo Leaves Typically Harvested?
    In China, the optimal harvesting period for Ginkgo leaves is from early August to late September, when the leaves are dark green, thick, and have the highest content of flavonoids and lactones.

    17. What Should Be Noted for Storing Harvested Ginkgo Leaves?
    After harvesting, Ginkgo leaves must not be exposed to direct sunlight and should be temporarily stored in a cool, shaded place with a pile thickness of 10–20 cm, turned frequently. Alternatively, they should be dried immediately. Dried leaves should be stored in a ventilated, low-temperature, dry indoor environment, such as a cold storage facility at 0–2°C with relative humidity below 50%, with regular ventilation to prevent mold and pests.

    18. Is There a Possibility of Adulteration in Ginkgo Biloba Extract?
    There is a possibility of adulteration. Rutin, as the cheapest flavonoid, may be added to Ginkgo extract to increase flavonoid content. However, in recent years, the Chinese Pharmacopoeia and United States Pharmacopeia have included rutin limit values in Ginkgo extract standards, significantly reducing the possibility of adulteration and its economic viability.

    19. Why Can Ginkgo, an Endangered Plant, Still Be Used as a Raw Material for Extraction?
    In China, Ginkgo leaves used for extraction come entirely from cultivated, non-wild sources. Additionally, when used for extraction, cultivated Ginkgo leaves must be registered and recorded with relevant authorities, subject to strict management.

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