L-CARNITINE
Fuel Energy, Support Metabolism Naturally
L-CARNITINE
L-Carnitine is a key nutrient aiding fatty acid transport into cells, boosting energy production. Ideal for active lifestyles, it supports metabolism, enhances exercise performance, and aids post-workout recovery. Made with high-purity ingredients, our formula ensures optimal absorption, helping you stay energized and vibrant daily.
Product name: L-Carnitine(L-Carnitine Base)
Molecular formula: C₇H₁₅NO₃
Starting material: Epichlorohydrin/Ethyl 4-chloroacetoacetate
Grade: Food/Feed Grade
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 25kg/drum
Derivatives:
- Acetyl-L-Carnitine hcl
- L-Carnitine Hcl
- L-Carnitine L-Tartrate
- L-Carnitine Fumarate
- Propionyl Carnitine Hcl
- Glycine Propionyl Carnitine Hcl
CAS#: 541-15-1
Molecular weight:161.20 g/mol
Source: Synthetic
Specification: 97%-103% Titrition
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irridiation
Carnitine series products exist in two primary stereoisomers: L-carnitine and D-carnitine, with distinct properties and applications.
L-carnitine is the biologically active configuration, naturally occurring in the body. It plays a key role in fatty acid transport into mitochondria for energy production, making it widely used in supplements for athletes, aiding workout performance and fat metabolism. It’s also added to infant formulas and clinical nutrition to support metabolic health.
D-carnitine, the inactive enantiomer, lacks physiological function. Worse, it may compete with L-carnitine for absorption, potentially inhibiting its activity. Thus, D-carnitine is not used in nutritional or therapeutic products.
Carnitine supplements, including L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine, offer versatile benefits for health and wellness.
These carnitine supplements also aid weight management by enhancing lipid oxidation and are used in nutritional formulas for infants. Trusted for their role in energy production, carnitine products cater to diverse needs, from athletes to those prioritizing metabolic and brain health.
The production of carnitine series, including key variants like L-carnitine, involves two primary processes using distinct starting materials: epichlorohydrin and ethyl 4-chloroacetoacetate, each with unique synthesis pathways.
The first process begins with epichlorohydrin, a versatile epoxide. Initially, epichlorohydrin undergoes amination with trimethylamine, forming a quaternary ammonium salt intermediate. This is followed by hydrolysis to introduce the hydroxyl group, yielding a racemic mixture of D,L-carnitine. Resolution via chiral reagents or enzymatic methods then separates L-carnitine, the biologically active form. This route is valued for its cost efficiency and scalability, making it widely used in industrial carnitine production, especially for L-carnitine supplements.
The second process starts with ethyl 4-chloroacetoacetate, a chlorinated ester. Here, the ester undergoes condensation with trimethylamine, forming a substituted β-ketoester. Subsequent hydrolysis and decarboxylation steps generate the carnitine backbone. Chiral induction during synthesis or post-synthesis resolution ensures the production of L-carnitine. This method offers high stereoselectivity, critical for pharmaceutical-grade carnitine products, and is favored for its precision in yielding pure L-carnitine, essential for applications in clinical nutrition and high-purity carnitine formulations.
Both processes prioritize optimizing yields and chiral purity, catering to diverse needs from bulk carnitine supplements to specialized pharmaceutical carnitine products, ensuring quality across the carnitine series.
Carnitine’s inherent hygroscopic nature—its tendency to absorb moisture from the air—shapes its terminal product designs, with hard capsules emerging as the primary form beyond drinkable formulations. Hard capsules, typically made of gelatin or plant-based shells, create a sealed barrier that shields carnitine powder from humidity, preserving potency and preventing clumping. This makes them ideal for stable, long-term storage and convenient dosing, widely adopted in carnitine supplements for fitness and metabolic support.
Liposomes and microcapsules, though less common, offer specialized solutions. Liposomal carnitine encases the nutrient in lipid bilayers, enhancing stability against moisture while boosting bioavailability. Microcapsules, using protective coatings like cellulose, further minimize moisture exposure, suiting niche applications such as controlled-release formulations. These forms address carnitine’s hygroscopicity, ensuring product integrity across storage and use, while catering to diverse consumer needs from daily supplementation to targeted nutrient delivery.
