Bulk Melatonin Supplier | Fermented & Synthetic

Bulk Melatonin for Advanced Sleep & Circadian Support Formulations
Manufactured under rigorous GMP and FSSC22000 standards.
Embodies the essence of pure, high-quality dietary supplement ingredients
MELATONIN
For a Deeper Sleep

Global B2B Supply for Premium Sleep-Support Formulations
Purecium is a premier global B2B supplier of high-purity, food-grade Melatonin powder. Synthesized naturally by the pineal gland to regulate the sleep-wake cycle, melatonin is the cornerstone of the modern sleep-aid industry. We strictly supply raw ingredients tailored for contract manufacturers (OEM/ODM) and terminal brands, ensuring uncompromising quality, scalable production (200–300 MT annually), and seamless global compliance.

Product name: Melatonin
Molecular formula: C13H16N2O2
Starting material: Diethyl malonate and acrylonitrile
Grade: Food grade
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 25kg/drum
CAS#: 73-31-4
Molecular weight:232.28 g/mol
Source: Synthetic/Fermentation
Specification: 98% HPLC
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation

Synthetic vs. Natural (Fermented) Melatonin
To meet diverse brand positioning and cost structures, Purecium provides two distinct sourcing options. Both deliver identical physical and chemical properties (≥ 98% purity) but cater to different market segments:

Origin & Source
Production Method
Best Suited For (B2B Applications)

Natural Fermentation (Phyto-Melatonin Alternative)
Derived from non-GMO corn using tryptophan as a substrate. Verified via Carbon-14 (C14) testing (biogenic carbon >97%).
Natural health product lines, and vegan sleep aids.

Chemical Synthesis
Traditional synthesis boasting a century-long safety record and highly efficient scalability.
Mainstream, high-volume commercial sleep aids prioritizing extreme cost-effectiveness.

Formulation Applicability & Synergistic Blends
Our Melatonin is engineered for versatility across modern dietary supplement formats, from standard tablets to the increasingly popular gummy and liquid formats.
Particle Size Precision: We supply standard 80-mesh powder for optimal blending in capsules and tablets, alongside ultrafine 300-mesh powder, specifically designed to improve dispersion for liquid applications and specialized rapid-delivery systems.
Synergistic Stability: Purecium’s melatonin resists hygroscopic clumping, maintaining excellent physical stability when blended with trending sleep-support ingredients such as Vitamin B6, GABA (for rapid neural calming), Magnesium, L-Theanine, and Valerian Root Extract.
Global Compliance & Supply Chain Security
We prioritize supply chain resilience for procurement managers globally. Our primary manufacturing origin in China guarantees stable pricing and uninterrupted long-term supply.
Regulatory Approvals: Our Melatonin is food-grade and recognized as an Old Dietary Ingredient (ODI) in the US. We provide comprehensive QA documentation to support smooth customs clearance for the European Union, the United Kingdom, and Canadian NHP registrations.
Stringent Purity: Utilizing only food-grade anhydrous ethanol, residual solvents are tightly capped at < 5,000 ppm (USP standard). Heavy metals strictly meet EU and USP limits (Lead < 0.5 ppm, Mercury < 0.1 ppm, Arsenic < 3 ppm, Cadmium < 1 ppm).
Purecium Melatonin Frequently Asked Questions (B2B FAQ)
Q1: Do you provide finished Melatonin products or white-label OEM services?
A: Purecium strictly supplies raw bulk ingredients to B2B distributors, contract manufacturers, and terminal brands. We do not engage in B2C retail. However, we partner with reliable CDMOs to facilitate end-to-end white-label services (tablets, capsules, softgels, and gummies) for our clients.
Q2: How can procurement teams verify the natural origin of your fermented Melatonin?
A: Origin verification is strictly conducted via Carbon-14 (C14) testing. Our fermented Melatonin, sourced from non-GMO corn, yields a bio-based carbon content exceeding 97%, definitively distinguishing it from synthetic alternatives. Full C14 test reports are available for your QA department.
Q3: What is your Minimum Order Quantity (MOQ) and packaging standard?
A: Our standard MOQ is 25 kg. It is industrially packed in a 25kg net weight drum (Dimensions: 40cm x 40cm x 50cm / Gross weight: 28 kg) to ensure optimal protection during global transit.
Q4: What is the shelf life, and do you supply stability data?
A: The shelf life is 24 months when stored tightly sealed in a dry, dark environment. We provide robust technical dossiers, including both accelerated and long-term stability test reports, to support your R&D formulations.
Q5: What are the shipping timelines for North America and the EU/UK?
A: For clients in the United States, Canada, and Mexico, we offer immediate 2-day pickup or door-to-door delivery from our US-based warehouses. Orders for the EU, UK, and other global regions are dispatched directly from our China facilities within one week.
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