NAD(Nicotinamide Adenine Dinucleotide)
Enhance Metabolism, Promote Longevity
Global B2B Supply of Premium NMN&NAD⁺ Raw Materials
Purecium is a leading global B2B supplier of high-purity Nicotinamide Adenine Dinucleotide (NAD / NAD⁺). As a critical coenzyme found in all living cells, NAD is the cornerstone of cellular energy (ATP) production, DNA repair, and sirtuin activation. We supply ultra-pure, food-grade NAD raw materials specifically tailored for contract manufacturers (OEM/ODM) and terminal brands developing advanced anti-aging, cognitive health, and metabolic support formulations.
Product name: NAD(Nicotinamide Adenine Dinucleotide)
Molecular formula: C₂₁H₂₇N₇O₁₄P₂
Starting material: Nicotinamide
Grade: Food grade
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 20/25 kg/drum
Product available:
- NAD(Nicotinamide Adenine Dinucleotide
- Nicotinamide Adenine Dinucleotide (Reduced Form)
- NAD Lipidosome
- NMN(Nicotinamide Mononucleotide)
- NR HCL
CAS#: 53-89-4
Molecular weight: 663.43 g/mol
Source: Enzymatic Synthesis
Specification: 98% HPLC
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation
Mechanism of Action: Energy Metabolism & Longevity
Unlike precursors such as NMN or NR, direct NAD supplementation requires precise formulation to deliver its profound physiological benefits:
- Mitochondrial ATP Production: NAD⁺ accepts electrons during glycolysis and the citric acid cycle, driving the electron transport chain to synthesize ATP—powering high-demand organs like the heart and brain.
- Sirtuin & PARP Activation: NAD⁺ serves as the essential substrate for sirtuins (longevity genes) and PARPs. It directly regulates cellular homeostasis, enhances genomic integrity by repairing DNA strand breaks, and mitigates age-related cellular decline.
Formulator's Guide: Overcoming NAD Instability
NAD is notoriously sensitive to environmental factors. Purecium provides the technical foundation and advanced material forms to help formulators overcome stability challenges:
- Standard Solid NAD (80-Mesh): Requires strict "Low Temperature + Moisture Protection + Light Avoidance." It must be stored refrigerated at 2–8°C to maintain a 24-month shelf life. Short-term (1-2 months) storage at 4°C is acceptable with strictly airtight packaging.
- Aqueous Solutions: Extremely unstable. Must be freshly prepared for immediate use, with temporary 4°C storage not exceeding 24 hours.
- The Liposomal Solution: To combat degradation and boost bioavailability, the industry standard is formulating NAD into liposomes. Purecium supports CDMO partners in creating highly stable Liposomal NAD formulations with a 50%–70% active ingredient payload, ensuring maximum absorption and shelf stability for retail products.
Procurement & Quality Assurance Fact Sheet
Purecium strictly adheres to international pharmaceutical and food-grade safety standards, ensuring smooth global customs clearance:
- Certifications: Manufactured under ISO9001, Kosher, Halal, and FSSC22000 standards.
- Purity & Solvents: Utilizes food-grade anhydrous ethanol, strictly controlling residual levels to < 5,000 ppm (USP standard).
- Heavy Metals (EU/USP Compliant): Lead < 0.5 ppm; Mercury < 0.1 ppm; Arsenic < 3 ppm; Cadmium < 1 ppm.
- Minimum Order Quantity (MOQ): Highly flexible. 1 kg MOQ available for R&D and pilot runs; standard commercial packaging is a 25kg/drum (Dimensions: 40x40x50cm).
- Global Logistics: Orders dispatch directly from our facilities in China via air freight or express courier, delivering globally within one week.
