Alpha-GPC — Premium Choline Donor for Cognitive Formulations
High Purity Crosses Blood-Brain Barrier
Embodies the essence of pure, high-quality dietary supplement ingredients
Alpha GPC(Alpha-Glycerophosphocholine)
Boost Brain Power, Enhance Focus

Alpha GPC(Alpha-Glycerophosphocholine)
Premium Alpha-GPC Raw Materials by Purecium
Purecium is a premier global B2B supplier of Alpha-GPC (Alpha-Glycerophosphocholine), a highly bioavailable choline source critical for acetylcholine production, cognitive enhancement (nootropics), and athletic performance. We supply raw ingredients to contract manufacturers and terminal brands globally, offering 98% powder, 50% powder, and 85% liquid forms. Sourced from either Non-GMO soy extraction or high-purity chemical synthesis, Purecium’s Alpha-GPC is FDA GRAS recognized, ISO9001, Kosher, and Halal certified. With a synthetic production capacity of 200 MT/year, we guarantee stable supply and rapid 2-day dispatch from our US warehouses.
Product name: ALPHA GPC(Alpha-Glycerophosphocholine)
Molecular formula: C₈H₂₀NO₆P
Starting material: (R)-(-)-3-Chloro-1,2-propanediol/Soybean
Grade: Food
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 25kg/drum
Carrier:
- Alpha GPC 50% DCP(Dibasic calcium phosphate)
- Alpha GPC 50% Maltodextrin(Water soluble)
CAS#: 28319-77-9
Molecular weight:257.22 g/mol
Source: Synthetic/Natural
Specification: 50%/85%/98% Titrition
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation

Procurement & Supply Chain Fact Sheet
At Purecium, we streamline the sourcing process for procurement teams with transparent supply chain metrics:
- Minimum Order Quantity (MOQ): 25 kg.
- Production Capacity: 200 MT/year (Synthetic route), ensuring uninterrupted long-term supply.
- Packaging Specifications: 25kg net weight per drum (Drum dimensions: 40cm x 40cm x 50cm, Gross weight: 28 kg).
- Physical Properties: 80-mesh fine white powder (for 50% and 98%) or clear liquid (for 85%).
- Global Logistics: 2-day pickup/delivery available from our US warehouses (for US, Canada, Mexico). Global shipments dispatch from China within 1 week.
- Quality & Safety: FDA GRAS, ISO9001, Kosher, Halal, FSSC22000. 24-month shelf life when stored in a tightly sealed, dry, and dark environment.
Formulation Guide: Specifications & Applications
Purecium offers diverse Alpha-GPC specifications tailored to specific manufacturing requirements, from solid dosages to cosmetic formulations.
Specification
Composition / Excipients
Application
Alpha GPC 50%(Water soluble)
50% Alpha-GPC + 50% Maltodextrin
Powdered drink mixes, sports beverages, and functional foods
Alpha GPC 50%(Standard)
50% Alpha-GPC + 49% DCP + 1% Silicon Dioxide
General wellness supplements, tablets, and hard capsules.
Alpha GPC 85%(Liquid)
85% Alpha-GPC + 15% Water
Liquid dietary supplements (syrups/tinctures) and Cosmetics.
Alpha GPC powder 98%
98% Alpha-GPC (Highest Purity)
Premium nootropics, memory support, and high-potency capsules.
Purecium Frequently Asked Questions (FAQ for B2B Buyers)
Q1: What are the primary sources of Purecium's Alpha-GPC, and how do their prices compare?
A: We offer Alpha-GPC from two distinct sources: natural extraction (from Non-GMO soybeans) and chemical synthesis (using CPD and phosphorylcholine). Because the natural enzymatic extraction process is more complex, the soy-derived Alpha-GPC is priced at approximately twice the cost of the synthetic version. Both meet rigorous cognitive health quality standards.
Q2: What is the difference between the two types of 50% Alpha-GPC powder you supply?
A: The difference lies in the excipients, which determine solubility. Our standard 50% Alpha-GPC uses Dihydrogen Calcium Phosphate (DCP, 49%) and Silicon Dioxide (1%), making it ideal for tablet and capsule manufacturing. If your formulation requires water solubility (e.g., for sports drinks), we supply a variant using Maltodextrin (50%) as the carrier.
Q3: What are the main applications for the 85% Liquid Alpha-GPC?
A: While our 50% and 98% powders are primarily used for dietary supplements (tablets, capsules, gummies), the 85% liquid form (which contains 15% water) is highly versatile. It is ideal for fast-acting liquid tinctures and is heavily utilized as an active raw material in the cosmetics industry for topical applications.
Q4: Is your Alpha-GPC safe and compliant for the US dietary supplement market?
A: Yes. Purecium’s Alpha-GPC is food-grade and is recognized as GRAS (Generally Recognized as Safe) by the FDA, making it fully compliant for use in dietary supplements, functional foods, and beverages in the US market.
Q5: Can Purecium provide finished OEM products, or only raw materials?
A: Purecium operates strictly as a B2B raw ingredient supplier for distributors, contract manufacturers, and terminal brands; we do not sell to individual consumers. However, we have strong partnerships with certified contract manufacturers and can facilitate comprehensive white-label OEM services, including Alpha-GPC tablets, hard capsules, softgels, and gummies.
Q6: What makes Alpha-GPC superior for nootropic and pre-workout formulations?
A: Alpha-GPC efficiently crosses the blood-brain barrier, directly supplying choline to synthesize acetylcholine. This makes it one of the most effective ingredients for enhancing memory, focus, and mental clarity (nootropics), while also supporting muscle control and power output for pre-workout sports nutrition.
Q7: How do you guarantee the purity of your synthetic Alpha-GPC?
A: Our synthetic route utilizes stereoselective purification and advanced chiral chromatography to isolate the highly active L-α isomer. This rigorous process yields a high-purity (98%) product that is completely suitable for high-end pharmaceutical and dietary supplement applications.
Q8: What documentation and stability testing do you provide?
A: We provide comprehensive documentation for every batch, including Certificates of Analysis (COA). Purecium also conducts and supplies data from both accelerated and long-term stability tests to support your product's shelf-life claims. Contact [email protected] for specific reports.
Q9: How should bulk Alpha-GPC powder be stored to prevent degradation?
A: Alpha-GPC, especially the 98% purity form, is sensitive to environmental factors. It must be stored in a tightly sealed container in a dry place, strictly away from direct light and moisture. When stored correctly, it maintains a shelf life of 24 months.
Q10: How do I initiate a bulk order or request pricing?
A: Procurement managers can contact our global sales team at [email protected]. With a low MOQ of 25kg and a dedicated U.S. warehouse, we ensure rapid pricing quotes and seamless supply chain integration for your next manufacturing run.
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