Bulk PQQ (Pyrroloquinoline Quinone) for Advanced Mitochondrial & Cognitive Health
High-water-solubility PQQ Disodium Salt.
Backed by 15 years of GMP & FSSC22000 manufacturing excellence.
Embodies the essence of pure, high-quality dietary supplement ingredients
PQQ (Pyrroloquinoline quinone)
Enhance Mitochondria, Promote Cellular Vitality

Global B2B Supply of Premium PQQ Raw Materials
Purecium is a premier global B2B supplier of high-purity Pyrroloquinoline Quinone (PQQ). Often referred to as a longevity coenzyme, PQQ is a potent bioactive compound that stimulates mitochondrial biogenesis, enhances cellular energy (ATP) production, and promotes Nerve Growth Factor (NGF) synthesis. We exclusively supply food-grade, highly bioavailable PQQ raw materials tailored for distributors, contract manufacturers (OEM/ODM), and terminal brands developing premium cognitive support, anti-aging, and cardiovascular health supplements.
Product name: PQQ(Pyrroloquinoline quinone disodium salt)
Molecular formula: C14H4N2Na2O8
Starting material: Corn
Grade: Food grade
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 25 kg/drum
Product available:
- PQQ(Pyrroloquinoline quinone disodium salt)
CAS#: 122628-50-6
Molecular weight: 374.17 g/mol
Source: Fermentation
Specification: 98% HPLC
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation

Core Clinical Mechanisms: Mitochondria & Cellular Vitality
- Mitochondrial Biogenesis & ATP Production: PQQ is one of the few known substances capable of stimulating the growth of new mitochondria in aging cells. It significantly boosts ATP production, effectively combating chronic fatigue and accelerating post-exercise recovery for sports nutrition brands.
- Neuroprotection & Cognitive Enhancement: By stimulating the synthesis of Nerve Growth Factor (NGF) and reducing neuroinflammation, PQQ preserves neuronal integrity, making it a cornerstone ingredient for nootropic and memory-support formulations.
- Potent Antioxidant Defense: PQQ continuously scavenges free radicals, protecting vascular endothelial cells from lipid peroxidation (reducing oxidized LDL-C) and supporting long-term cardiovascular and hepatic (liver) health.
Procurement & Quality Assurance Fact Sheet
Purecium strictly adheres to international pharmaceutical and food-grade safety standards. Our PQQ is derived via advanced microbial fermentation utilizing Non-GMO corn.
- Regulatory Status: Fully food-grade and officially recognized under FDA GRAS (GRN590).
- Certifications: Manufactured under ISO9001, Kosher, Halal, and FSSC22000 standards.
- Solvents & Heavy Metals (EU/USP Compliant): Processed exclusively with food-grade anhydrous ethanol (< 5,000 ppm residual). Lead < 0.5 ppm; Mercury < 0.1 ppm; Arsenic < 3 ppm; Cadmium < 1 ppm.
- Minimum Order Quantity (MOQ): Highly flexible 1 kg MOQ for R&D; standard industrial packing is a 25kg/drum.
Feature
Pure PQQ (Free Acid)
PQQ Disodium Salt
Water Solubility
Highly insoluble in water.
Excellent water solubility, ensuring uniform dispersion in formulations.
Bioavailability
Low absorption rate in the human digestive tract.
High absorption rate, maximizing the physiological benefits.
B2B Application
Rarely used in commercial dietary supplements.
The industry standard for hard capsules, liposomes, and functional beverages.
Purecium PQQ Frequently Asked Questions (B2B FAQ)
Q1: What is the exact chemical form of the PQQ you supply?
A: We supply PQQ Disodium Salt. Because pure Pyrroloquinoline Quinone is insoluble in water, the disodium salt form is engineered to provide superior stability, water solubility, and biological absorption, making it the preferred choice for commercial supplement manufacturing.
Q2: Is your PQQ manufactured using synthetic chemicals or natural processes?
A: Our PQQ is produced through a highly controlled, natural bacterial fermentation process utilizing Non-GMO corn as the starting substrate, ensuring a clean, sustainable, and highly pure final product.
Q3: What is the regulatory and safety status of your PQQ?
A: PQQ Disodium Salt is 100% food-grade and holds a self-affirmed Generally Recognized As Safe (GRAS) status under FDA notification GRN590.
Q4: Do you offer white-label manufacturing or sell finished PQQ products?
A: Purecium strictly operates as a raw material supplier for B2B procurement managers, distributors, and terminal brands. While we do not sell finished products to consumers, we partner with certified CDMOs to facilitate white-label services (e.g., hard capsules, liposomal PQQ) for our B2B clients.
Q5: What is the physical appearance and mesh size of the powder?
A: Purecium’s PQQ Disodium Salt presents as a fine, reddish-brown powder standardized to an 80-mesh size, ensuring excellent flowability for encapsulation.
Q6: What is your Minimum Order Quantity (MOQ) and standard packaging?
A: Our standard commercial packaging is a 25kg net weight drum (Dimensions: 40cm x 40cm x 50cm). However, to support R&D and pilot runs, we offer a highly flexible MOQ of just 1 kg.
Q7: How are residual solvents and heavy metals controlled?
A: Quality is our top priority. We use only food-grade anhydrous ethanol, capping residues below 5,000 ppm. Heavy metals strictly adhere to EU and USP limits (Lead <0.5 ppm, Arsenic <3 ppm).
Q8: What are the storage requirements and shelf life for bulk PQQ?
A: To guarantee a standard shelf life of 24 months, bulk PQQ powder must be stored in a tightly sealed, dry environment, strictly protected from light and excessive moisture.
Q9: What is the typical delivery timeframe for international orders?
A: All global bulk orders are dispatched directly from our highly certified facilities in China. Whether shipping via air freight or express courier, we ensure delivery within one week of order placement.
Q10: What quality certifications accompany your PQQ raw materials?
A: Our manufacturing processes are rigorously audited. We provide comprehensive documentation, including ISO9001, Kosher, Halal, and FSSC22000 certifications, along with batch-specific Certificates of Analysis (COA).
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