Q1. What is magnesium bisglycinate and what is it used for in dietary supplements?

Magnesium bisglycinate, also called magnesium glycinate, is a chelated form of magnesium bound to two glycine molecules, used in supplements for sleep, stress, muscle and bone health support. It carries CAS 14783-68-7, molecular formula C4H8MgN2O4, molecular weight 172.42 g/mol and approximately 14% elemental magnesium. Typical servings supply 100 mg to 400 mg elemental magnesium per day.

Q2. What is the difference between magnesium bisglycinate and magnesium glycinate?

There is no chemical difference: magnesium bisglycinate and magnesium glycinate are two trade names for the same compound, the 2:1 chelate of glycine with magnesium, CAS 14783-68-7. 'Bisglycinate' emphasizes the two glycine molecules bound per magnesium ion, while 'glycinate' is the shorter generic name. Purecium's specification documents both names so that buyers can match either nomenclature on their own systems.

Q3. How do I know the product is a true chelate and not a mixture?

The definitive check is chelation verification. Purecium tests every batch by spectroscopic methods such as Fourier-transform infrared spectroscopy, which detects the characteristic metal-amino-acid coordination bonds of a true chelate. A Certificate of Analysis should state the chelation verification method; genuine fully-reacted magnesium bisglycinate behaves differently from a physical blend of magnesium salt and glycine in these analyses.

Q4. How much elemental magnesium does magnesium bisglycinate provide?

Magnesium bisglycinate provides approximately 14% elemental magnesium by weight, calculated from the molecular formula C4H8MgN2O4 with molecular weight 172.42 g/mol. This means that to supply 200 mg of elemental magnesium a formulator needs approximately 1.4 g of the chelate. The exact assay is reported on each batch Certificate of Analysis.

Q5. Why is magnesium bisglycinate considered gentle and well absorbed?

Because the magnesium ion is tightly bound within the glycine chelate, it is released gradually rather than dissociating aggressively in the digestive tract, which contributes to the chelate's characteristically gentle profile. Published research indicates efficient absorption of amino-acid chelated magnesium, and the NIH Office of Dietary Supplements recognizes magnesium's role in normal muscle and nerve function. It is a preferred form for sensitive consumers.

Q6. What does a fully-reacted chelate mean for product quality?

Fully-reacted means the magnesium and glycine have formed a true coordination complex rather than remaining as an unreacted mixture. This matters because the chelated structure is what delivers the gentle, well-absorbed profile of magnesium bisglycinate. Purecium confirms reaction completeness on every batch by spectroscopic analysis and reports the result in the quality documentation.

Q7. What are the typical applications of magnesium bisglycinate in finished products?

Magnesium bisglycinate is used in sleep-support and evening formulas, stress and calm products, muscle-relaxation and recovery blends, and bone health supplements alongside vitamin D3 and calcium. Typical servings supply 100 mg to 400 mg elemental magnesium per day. The chelate suits capsules, tablets, stick-packs and powders.

Q8. Can magnesium bisglycinate be combined with other ingredients?

Yes. Common pairings are L-theanine, glycine and herbal extracts such as ashwagandha for sleep and calm formulas, vitamin D3 and calcium for bone health, and taurine for muscle support. Because the chelate has a neutral taste, it blends well into capsules and powders. Formulators should verify ingredient compatibility and calculate total elemental magnesium across the formula.

Q9. Is magnesium bisglycinate vegan?

Yes. Purecium's magnesium bisglycinate is produced from synthetic glycine and a food-grade magnesium source with no animal-derived materials, carriers or processing aids. It carries clear vegan, non-GMO, allergen-free and gluten-free statements and is suitable for vegan and vegetarian formulations.

Q10. What is the role of glycine in the chelate?

Glycine is the smallest amino acid and serves as the ligand that binds magnesium in a 2:1 ratio, forming the stable chelate. Glycine itself is studied for calming and sleep-support properties, which complement magnesium's roles in nervous-system and muscle function. The glycine content is part of the identity of the chelate and is confirmed on the specification.

Q11. How is identity and purity verified for magnesium bisglycinate?

Identity is confirmed by magnesium and glycine identification together with the characteristic infrared spectrum of the chelate. Elemental magnesium is quantified by titration or atomic absorption/ICP methods, chelation completeness by spectroscopy, and each batch is tested for heavy metals and microbial limits, all reported on the Certificate of Analysis.

Q12. What quality documentation should I request when sourcing magnesium bisglycinate?

Request a current specification sheet, a batch-specific Certificate of Analysis showing identification, elemental magnesium assay, chelation verification result, heavy metals and microbial results, an SDS, allergen and gluten statements, and non-GMO declarations. Also request Kosher and Halal certificates, ISO 9001 and FSSC 22000 certificates, and stability data for registration.

Q13. What is the MOQ and lead time for magnesium bisglycinate from Purecium?

The minimum order quantity is 25 kg. The chelate is packed in 25 kg drums with food-grade polyethylene inner bags, and samples and technical documentation are available before you commit. Standard production lead time is typically 7 to 15 working days after order confirmation, with faster dispatch for stocked items. For North American customers, Purecium holds inventory at its US warehouse, enabling pickup or delivery within approximately two days.

Q14. How should magnesium bisglycinate be stored, and what is the shelf life?

Store in tightly sealed original containers in a cool, dry place below 25 degrees Celsius, protected from moisture and heat. The chelate is stable under these conditions, and shelf life is generally 36 months from the date of manufacture. Each shipment's CoA states the production date and expiry date for inventory planning.

Q15. Why should we source magnesium bisglycinate from Purecium?

Purecium supplies fully-reacted magnesium bisglycinate chelate with every batch released on a full Certificate of Analysis including identification, elemental magnesium assay, chelation verification, heavy metal and microbial results, an SDS and supporting documentation. Production follows ISO 9001 and FSSC 22000 certified systems with Kosher and Halal certification available. The minimum order is 25 kg, inventory is staged at our US warehouse for fast fulfillment, and global delivery covers Hong Kong, mainland China, the EU and beyond. For long-term supply relationships, Purecium provides consistent quality, batch traceability, regulatory documents and direct technical communication.

Magnesium Bisglycinate Chelate Powder: Fully-Reacted

Magnesium Bisglycinate Chelate for Sleep, Stress and Muscle Health Supplement Formulas
Fully-Reacted Amino-Acid Chelate Produced Under ISO 9001 and FSSC 22000 Systems
Embodies the essence of pure, high-quality dietary supplement ingredients
Magnesium Bisglycinate / Magnesium Glycinate Chelate Powder
Gentle High-Absorption Glycine Chelate

Magnesium Bisglycinate
Purecium Magnesium Bisglycinate is a fully-reacted amino-acid chelate of magnesium and glycine, also sold under the name magnesium glycinate, and supplied as a B2B raw material with CAS 14783-68-7, molecular formula C4H8MgN2O4, molecular weight 172.42 g/mol and approximately 14% elemental magnesium. The chelate is produced by reaction of food-grade glycine with a food-grade magnesium source under controlled conditions, forming a stable 2:1 glycine-magnesium complex. Each batch is tested for identity, chelation completeness, assay, heavy metals and microbial limits. Allergen-free, gluten-free, non-GMO and vegan, it is packed in 25 kg drums with a 25 kg minimum order and full B2B documentation.

Product name: Magnesium Bisglycinate (Magnesium Glycinate)
Molecular formula: C₄H₈MgN₂O₄
Starting material: Glycine + food-grade magnesium source (chelation)
Grade: Food Grade (chelated)
Heavy Metals: Conforms to USP/EP limits
Pesticide residue: Conforms to USP/EP limits
Packing size: 25kg/drum
CAS#: 14783-68-7
Molecular weight: 172.42 g/mol
Source: Synthetic (glycine chelate)
Specification: Magnesium bisglycinate chelate; Mg approx. 14%
Country of origin: China
Residual solvent: Conforms to USP/EP limits
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation:

Magnesium Bisglycinate Overview

Magnesium bisglycinate, also known as magnesium glycinate, is a chelated form of magnesium in which the mineral is bound to two glycine molecules, used in dietary supplements for sleep, stress, muscle and general wellness support. The chelate carries CAS 14783-68-7, molecular formula C4H8MgN2O4, molecular weight 172.42 g/mol and approximately 14% elemental magnesium.

For the dietary supplement industry, magnesium bisglycinate is valued for its gentle profile on the digestive system and its efficient absorption, which make it a preferred magnesium form for premium sleep, calm and muscle-relaxation formulas. Purecium supplies magnesium bisglycinate chelate as a B2B raw material for distributors, contract manufacturers, private-label producers and finished supplement brands.

Source & Ingredient Identity

Purecium Magnesium Bisglycinate is produced by the controlled reaction of food-grade glycine with a food-grade magnesium source, forming a stable 2:1 amino-acid chelate, followed by drying and milling to a fine powder. Chelation completeness is verified analytically, because a fully-reacted chelate is what distinguishes genuine magnesium bisglycinate from simple physical mixtures of magnesium salts and glycine.

The declared product is magnesium bisglycinate (magnesium glycinate), CAS 14783-68-7, and the two names are used interchangeably in the trade for the same chelate. For B2B purchasing, the critical checks are the chelation state and method of verification, the elemental magnesium assay, glycine content, heavy metal profile and the manufacturing process.

Key Characteristics of Magnesium Bisglycinate

1. Fully-reacted amino-acid chelate. The defining characteristic of magnesium bisglycinate is its chelated structure, in which magnesium is bound within a stable 2:1 glycine complex. This is verified by methods including infrared spectroscopy, which distinguishes a true chelate from an unreacted salt-and-amino-acid blend.

2. Gentle, well-absorbed magnesium. Because the mineral is bound to glycine, the chelate does not dissociate aggressively in the digestive tract, which contributes to its characteristically gentle profile; the NIH Office of Dietary Supplements recognizes magnesium's role in normal muscle and nerve function, and EFSA has authorized health claims for the mineral in the EU. Finished-product claims should follow the regulations of the destination market.

3. Clean, stable powder profile. The chelate is a free-flowing off-white powder that is non-GMO, allergen-free, gluten-free and vegan, with a neutral taste that is easily formulated into capsules, tablets, stick-packs and powders.

Magnesium Bisglycinate Manufacturing

The manufacturing process begins with the reaction of food-grade glycine with a food-grade magnesium source under precisely controlled temperature and pH to drive complete chelation, followed by concentration, drying and milling to specification. Every stage is process-controlled with in-process checks on reaction completeness, moisture and particle size.

Each finished lot is tested for identity, elemental magnesium assay, chelation completeness, heavy metals and microbial limits, all reported on the batch Certificate of Analysis. Each lot is traceable from raw materials to finished drum, and analytical methods follow current compendial approaches for amino-acid chelates, including USP-NF guidance where applicable.

Applications of Magnesium Bisglycinate

Sleep, stress and calm support is the primary application of magnesium bisglycinate. Mechanistically, magnesium supports normal nervous-system function and muscle relaxation, and the glycine ligand itself is an amino acid studied for its calming properties; the NIH Office of Dietary Supplements recognizes magnesium's physiological roles, and EFSA has authorized health claims for the mineral covering normal psychological and nervous-system function. Typical supplement servings supply 100 mg to 400 mg elemental magnesium per day.

Muscle and recovery products form the second cluster. Magnesium bisglycinate is used in evening muscle-relaxation and post-exercise recovery blends, and in bone health products alongside vitamin D3, calcium and other minerals. The chelate suits capsules, tablets, stick-packs and powders.

Formulators should note the approximately 14% elemental magnesium content when calculating label doses. Because of its neutral taste and gentle profile, the chelate is well suited to powders and stick-packs without requiring heavy flavor masking.

Manufacturing & Quality Control

Purecium Magnesium Bisglycinate is produced in facilities operating under ISO 9001 and FSSC 22000 certified quality systems, with Kosher and Halal certification available. Chelation completeness is verified on every batch using spectroscopic methods, and elemental magnesium is quantified by titration or atomic absorption/ICP methods.

Each commercial lot is fully traceable from raw materials to finished drum, and the batch is released only when identity, assay, chelation completeness, heavy metals and microbial results are all within specification. Alongside the CoA, Purecium provides the specification sheet, SDS, allergen and gluten statements, non-GMO declarations and stability data on request.

Magnesium Bisglycinate for B2B Supplement Manufacturing

Purecium supplies Magnesium Bisglycinate exclusively as a B2B raw material for distributors, contract manufacturers, private-label producers and finished supplement brands. The minimum order quantity is 25 kg; the chelate is packed in 25 kg drums with food-grade polyethylene inner bags, and samples and full documentation are available before commitment.

For North American customers, inventory is staged at Purecium's US warehouse, enabling pickup or delivery within approximately two days. Global delivery covers Hong Kong, mainland China, the EU and other regions, with export documentation prepared for every shipment. Purecium also provides chelation verification data, application guidance and technical and regulatory communication to support formulation and registration.

Reviewed by the Chief Quality Assurance / Regulatory Affairs Specialist at Purecium for technical accuracy and regulatory alignment.
Magnesium Bisglycinate Frequently Asked Questions (FAQ) for B2B Buyers

Q1. What is magnesium bisglycinate and what is it used for in dietary supplements?
Magnesium bisglycinate, also called magnesium glycinate, is a chelated form of magnesium bound to two glycine molecules, used in supplements for sleep, stress, muscle and bone health support. It carries CAS 14783-68-7, molecular formula C4H8MgN2O4, molecular weight 172.42 g/mol and approximately 14% elemental magnesium. Typical servings supply 100 mg to 400 mg elemental magnesium per day.
Q2. What is the difference between magnesium bisglycinate and magnesium glycinate?
There is no chemical difference: magnesium bisglycinate and magnesium glycinate are two trade names for the same compound, the 2:1 chelate of glycine with magnesium, CAS 14783-68-7. 'Bisglycinate' emphasizes the two glycine molecules bound per magnesium ion, while 'glycinate' is the shorter generic name. Purecium's specification documents both names so that buyers can match either nomenclature on their own systems.
Q3. How do I know the product is a true chelate and not a mixture?
The definitive check is chelation verification. Purecium tests every batch by spectroscopic methods such as Fourier-transform infrared spectroscopy, which detects the characteristic metal-amino-acid coordination bonds of a true chelate. A Certificate of Analysis should state the chelation verification method; genuine fully-reacted magnesium bisglycinate behaves differently from a physical blend of magnesium salt and glycine in these analyses.
Q4. How much elemental magnesium does magnesium bisglycinate provide?
Magnesium bisglycinate provides approximately 14% elemental magnesium by weight, calculated from the molecular formula C4H8MgN2O4 with molecular weight 172.42 g/mol. This means that to supply 200 mg of elemental magnesium a formulator needs approximately 1.4 g of the chelate. The exact assay is reported on each batch Certificate of Analysis.
Q5. Why is magnesium bisglycinate considered gentle and well absorbed?
Because the magnesium ion is tightly bound within the glycine chelate, it is released gradually rather than dissociating aggressively in the digestive tract, which contributes to the chelate's characteristically gentle profile. Published research indicates efficient absorption of amino-acid chelated magnesium, and the NIH Office of Dietary Supplements recognizes magnesium's role in normal muscle and nerve function. It is a preferred form for sensitive consumers.
Q6. What does a fully-reacted chelate mean for product quality?
Fully-reacted means the magnesium and glycine have formed a true coordination complex rather than remaining as an unreacted mixture. This matters because the chelated structure is what delivers the gentle, well-absorbed profile of magnesium bisglycinate. Purecium confirms reaction completeness on every batch by spectroscopic analysis and reports the result in the quality documentation.
Q7. What are the typical applications of magnesium bisglycinate in finished products?
Magnesium bisglycinate is used in sleep-support and evening formulas, stress and calm products, muscle-relaxation and recovery blends, and bone health supplements alongside vitamin D3 and calcium. Typical servings supply 100 mg to 400 mg elemental magnesium per day. The chelate suits capsules, tablets, stick-packs and powders.
Q8. Can magnesium bisglycinate be combined with other ingredients?
Yes. Common pairings are L-theanine, glycine and herbal extracts such as ashwagandha for sleep and calm formulas, vitamin D3 and calcium for bone health, and taurine for muscle support. Because the chelate has a neutral taste, it blends well into capsules and powders. Formulators should verify ingredient compatibility and calculate total elemental magnesium across the formula.
Q9. Is magnesium bisglycinate vegan?
Yes. Purecium's magnesium bisglycinate is produced from synthetic glycine and a food-grade magnesium source with no animal-derived materials, carriers or processing aids. It carries clear vegan, non-GMO, allergen-free and gluten-free statements and is suitable for vegan and vegetarian formulations.
Q10. What is the role of glycine in the chelate?
Glycine is the smallest amino acid and serves as the ligand that binds magnesium in a 2:1 ratio, forming the stable chelate. Glycine itself is studied for calming and sleep-support properties, which complement magnesium's roles in nervous-system and muscle function. The glycine content is part of the identity of the chelate and is confirmed on the specification.
Q11. How is identity and purity verified for magnesium bisglycinate?
Identity is confirmed by magnesium and glycine identification together with the characteristic infrared spectrum of the chelate. Elemental magnesium is quantified by titration or atomic absorption/ICP methods, chelation completeness by spectroscopy, and each batch is tested for heavy metals and microbial limits, all reported on the Certificate of Analysis.
Q12. What quality documentation should I request when sourcing magnesium bisglycinate?
Request a current specification sheet, a batch-specific Certificate of Analysis showing identification, elemental magnesium assay, chelation verification result, heavy metals and microbial results, an SDS, allergen and gluten statements, and non-GMO declarations. Also request Kosher and Halal certificates, ISO 9001 and FSSC 22000 certificates, and stability data for registration.
Q13. What is the MOQ and lead time for magnesium bisglycinate from Purecium?
The minimum order quantity is 25 kg. The chelate is packed in 25 kg drums with food-grade polyethylene inner bags, and samples and technical documentation are available before you commit. Standard production lead time is typically 7 to 15 working days after order confirmation, with faster dispatch for stocked items. For North American customers, Purecium holds inventory at its US warehouse, enabling pickup or delivery within approximately two days.
Q14. How should magnesium bisglycinate be stored, and what is the shelf life?
Store in tightly sealed original containers in a cool, dry place below 25 degrees Celsius, protected from moisture and heat. The chelate is stable under these conditions, and shelf life is generally 36 months from the date of manufacture. Each shipment's CoA states the production date and expiry date for inventory planning.
Q15. Why should we source magnesium bisglycinate from Purecium?
Purecium supplies fully-reacted magnesium bisglycinate chelate with every batch released on a full Certificate of Analysis including identification, elemental magnesium assay, chelation verification, heavy metal and microbial results, an SDS and supporting documentation. Production follows ISO 9001 and FSSC 22000 certified systems with Kosher and Halal certification available. The minimum order is 25 kg, inventory is staged at our US warehouse for fast fulfillment, and global delivery covers Hong Kong, mainland China, the EU and beyond. For long-term supply relationships, Purecium provides consistent quality, batch traceability, regulatory documents and direct technical communication.
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