Alpha-Ketoglutarate (AKG) — Premium Krebs Cycle Intermediate for Longevity & Sports Nutrition Formulations
Fermentation-Derived AKG
Embodies the essence of pure, high-quality dietary supplement ingredients
AKG(Alpha - Ketoglutaric Acid)
Metabolic Support and Energy Enhancer

Premium Alpha-Ketoglutarate (AKG) Raw Materials by Purecium
Purecium is a trusted global B2B supplier of high-purity Alpha-Ketoglutarate (AKG) and its advanced salt forms (Calcium AKG, Magnesium AKG, Sodium AKG). Derived from Non-GMO corn through advanced microbial fermentation, our AKG is a 100% natural, clean-label intermediate of the Krebs cycle, widely utilized in sports nutrition (fatigue recovery) and longevity/anti-aging supplements (bone health and metabolic support). Manufactured under strict ISO9001 and FSSC22000 standards, our 80-mesh fine white powder ensures exceptionally low heavy metal and solvent residues, ready for global dispatch with a standard MOQ of 25kg.
Product name: AKG(Alpha - Ketoglutaric Acid)
Molecular formula: C6H5O6
Starting material: Corn
Grade: Food grade
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 25kg/drum
Product available:
- AKG(Alpha - Ketoglutaric Acid)
- Calcium AKG(Calcium Alpha - Ketoglutaric Acid)
- Magnesium AKG(Magnesium Alpha - Ketoglutaric Acid)
- Sodium AKG(Sodium Alpha - Ketoglutaric Acid)
CAS#: 328-50-7
Molecular weight:146.1 g/mol
Source: Natural source
Specification: 98% HPLC
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation

Manufacturing Excellence: The Fermentation Advantage
Purecium explicitly utilizes advanced Microbial Fermentation rather than traditional chemical synthesis to produce our AKG.
- Natural Source: We use renewable, Non-GMO corn as our starting carbon source.
- Zero Harsh Chemicals: Unlike chemical synthesis which relies on extreme temperatures and toxic catalysts, our biological fermentation operates under mild conditions, completely eliminating harmful chemical residues.
- High Biocompatibility: The fermentation process yields AKG that perfectly matches the natural structure found in the human body, ensuring maximum bioavailability and making it a true natural dietary ingredient.
Formulator's Guide to AKG Salts
To enhance formulation versatility, stability, and targeted health benefits, Purecium supplies AKG in various premium salt forms:
Product Form
Key Physiological Benefits
Application
Pure AKG base
Enhances mitochondrial ATP production; reduces physical/mental exhaustion.
Core ingredient for energy drinks and pre-workout fatigue recovery.
Calcium AKG
Mitigates calcium loss, supports bone matrix formation, and promotes longevity.
Anti-aging formulations, osteoporosis support, and premium longevity capsules.
Magnesium AKG
Combines energy production with muscle relaxation and nerve support.
Post-workout muscle recovery, sleep optimization, and cramp prevention.
Sodium AKG
Highly soluble metabolic support.
Specialized liquid metabolic or pharmaceutical applications.
Frequently Asked Questions for QA & Procurement
Q1: Is Purecium's Alpha-Ketoglutarate (AKG) considered a natural or synthetic product?
A: Our AKG is a 100% natural product. It is produced exclusively through microbial fermentation using Non-GMO corn as the starting material, rather than through chemical synthesis. This ensures a clean, bio-identical compound ideal for premium dietary supplements.
Q2: What are the specific heavy metal limits for your AKG products?
A: Our AKG strictly complies with both EU and USP standards for heavy metals. The limits are rigorously controlled as follows: Lead (Pb) < 0.5 ppm; Arsenic (As) < 3 ppm; Cadmium (Cd) < 1 ppm; Mercury (Hg) < 0.1 ppm.
Q3: Are there any solvent residues in your AKG, and what is the mesh size?
A: We use food-grade anhydrous ethanol during the production process. The residual ethanol level is strictly controlled to be under 5,000 ppm, fully complying with USP standards. The finished product is processed into a highly soluble 80-mesh fine white powder.
Q4: Does Purecium supply finished retail AKG products or offer OEM services?
A: Purecium operates strictly as a B2B supplier of raw nutritional ingredients to distributors, contract manufacturers, and terminal brands. While we do not sell retail products, we partner with premier contract manufacturers to provide end-to-end white-label OEM services for AKG tablets, hard capsules, softgels, and energy gummies.
Q5: What is the Minimum Order Quantity (MOQ) and packaging standard?
A: Our standard MOQ is 25 kg. The AKG powder is securely packed in 25kg drums (Dimensions: 40cm x 40cm x 50cm; Gross weight: 28 kg) with protective inner liners to maintain absolute purity during global transit.
Q6: What are the shipping terms and estimated delivery times?
A: All bulk orders are shipped directly from our manufacturing facilities in China. For global B2B clients, dispatch and delivery are typically arranged and completed within one week of the order confirmation.
Q7: Can Purecium guarantee a stable, long-term supply of AKG?
A: Yes. By utilizing scalable microbial fermentation technology and renewable raw materials (corn), Purecium maintains robust production capabilities, guaranteeing a consistent and long-term supply for large-scale contract manufacturers without price volatility.
Q8: What quality certifications does Purecium hold for AKG production?
A: Our manufacturing facilities are highly regulated and certified. We provide full documentation including ISO9001, Kosher, Halal, and FSSC22000 certifications for our Alpha-Ketoglutarate raw materials.
Q9: Do you provide COAs and stability reports for formulation validation?
A: Absolutely. We provide batch-specific Certificates of Analysis (COA) along with comprehensive data from both accelerated and long-term stability tests. Formulators and QA teams can request these reports directly by contacting [email protected].
Q10: What are the optimal storage conditions and shelf life for bulk AKG?
A: To maintain product integrity, AKG powder must be stored in a tightly sealed container in a cool, dry place, strictly away from direct light. Under these optimal conditions, the product has a guaranteed shelf life of 24 months.
INQUIRY FORM
Let's Discuss Your Needs
Address: Room 509, The cloud 111 Tung chua ST, Tai kok TSUI, HONG KONG.
Global network:
Hong Kong|Mainland China
EU: Netherlands
US: California| New York
