Bulk 5-HTP Powder Supplier | Peak X Free & Fermented

Premium 5-HTP Raw Materials for Global Brands
Pioneering high-purity natural extract and bio-fermented 5-HTP solutions to empower the world’s leading wellness and cognitive health brands.
Embodies the essence of pure, high-quality dietary supplement ingredients
5-HTP(5-Hydroxytryptophan)
Calm Mood, Restful Sleep

Bulk 5-HTP Supply for Contract Manufacturers & Terminal Brands
Purecium is a premier global B2B supplier of high-purity 5-HTP (5-Hydroxytryptophan), a vital serotonin precursor utilized extensively in mood regulation, stress relief, and sleep support formulations. We supply premium 5-HTP to distributors, contract manufacturers, and terminal brands worldwide. Recognizing the diverse needs of modern supplement formulations, we offer two distinct sourcing options: traditional Griffonia simplicifolia seed extract and highly cost-effective fermentation-sourced 5-HTP derived from Non-GMO corn. Manufactured under strict ISO9001 and FSSC22000 standards, our 80-mesh fine white powder ensures exceptional quality, seamless integration for solid dosages, and reliable global supply.

Product name: 5-HTP(5-Hydroxytryptophan)
Molecular formula: C₁₁H₁₂N₂O₃
Starting material: Corn/Griffonia simplicifolia
Grade: Food grade
Heavy Metals: USP/EP
Pesticide residue: USP/EP
Packing size: 25kg/drum
CAS#: 56-69-9
Molecular weight:220.22 g/mol
Source: Fermentation/Natural
Specification: 98% HPLC
Country of origin: China
Residual solvent: USP/EP
Allergen free/Gluten-free/Non-GMO/Vegan/Non-Irradiation

Fermented vs. Natural Extract 5-HTP
Both our natural extract and fermented 5-HTP achieve an industry-leading purity of 98% and possess identical physical and chemical properties. For procurement teams aiming to optimize costs without compromising quality, understanding the sourcing difference is key:

Feature
Fermentation-Sourced 5-HTP
Natural Extract (Griffonia Seed)

Starting Material.
Non-GMO Corn (Sustainable agricultural source)
Griffonia simplicifolia seeds (Native to West Africa).

Production Method
Advanced microbial bioconversion in a highly controlled, sterile environment.
Mechanical grinding followed by selective solvent extraction.

Cost-Effectiveness
Lower. Approximately 50% lower cost due to scalable, year-round production.
High. Subject to seasonal harvesting and geographic supply chain constraints.

Identification
Both sources can be precisely distinguished and verified using HPTLC analysis.
Both sources can be precisely distinguished and verified using HPTLC analysis.

Quality Assurance: The "Peak X Free" Guarantee
In the late 1980s, an outbreak of Eosinophilia-myalgia syndrome (EMS) was linked to an impurity known as 1,1'-ethylidene-bis-L-tryptophan (EBT) in L-tryptophan supplements. In HPLC chromatograms, this unknown impurity signal appears as a distinct peak, widely referred to in the industry as "Peak X."At Purecium, safety is our ultimate priority. We utilize state-of-the-art purification technology—enhanced chromatography for our natural extracts and tightly controlled metabolic environments for our fermented sources. We guarantee that all Purecium 5-HTP products, regardless of their source, are strictly "Peak X Free," completely eliminating the risk of EBT contamination and ensuring full compliance for the European and North American markets.
Procurement & Supply Chain Fact Sheet
Minimum Order Quantity (MOQ): 25 kg.
Packaging: 25kg net weight per drum (Dimensions: 40cm x 40cm x 50cm, Gross: 28 kg).
Physical Properties: 80-mesh fine white powder.
Shelf Life: 24 months (Store tightly sealed in a cool, dark, and dry environment).
Logistics: 2-day pickup from our US warehouses for clients in the US, Canada, and Mexico. Global shipments dispatch from China within one week.
Compliance: ISO9001, Kosher, Halal, and FSSC22000 certified. Accelerated and long-term stability reports available upon request
Purecium 5-HTP Frequently Asked Questions (B2B FAQ)
Q1: Do you provide finished 5-HTP retail products or white-label OEM services?
A: Purecium strictly supplies raw bulk ingredients to B2B clients, including terminal brands and contract manufacturers. We do not sell retail products. However, through our network of certified contract manufacturing partners, we can facilitate end-to-end white-label services for finished 5-HTP tablets, hard/soft capsules, gummies, and sports drinks.
Q2: How does the cost of synthetic 5-HTP compare to your fermented and natural extract options?
A: Synthetic 5-HTP exists but is priced similarly to the more expensive natural extract. Because our non-GMO fermented 5-HTP offers identical 98% purity at approximately half the cost—and is immune to the agricultural supply chain bottlenecks of Griffonia seeds—the market demand for synthetic 5-HTP has become negligible.
Q3: Can your fermented 5-HTP trigger Peak X impurities?
A: No. In fact, fermentation inherently simplifies Peak X management. By utilizing non-GMO corn substrates in a sterile microbial environment, we eliminate complex plant-based co-extracts from the outset. Combined with our targeted purification, our fermented 5-HTP is definitively Peak X Free.
Q4: Is your 5-HTP supply vulnerable to seasonal shortages?
A: While natural Griffonia seed extracts can be impacted by West African agricultural seasons, our fermentation-sourced 5-HTP ensures absolute supply chain resilience. We guarantee a consistent, high-volume, long-term supply year-round.
Q5: What technical documentation accompanies your bulk 5-HTP orders?
A: Every batch is supported by comprehensive documentation, including Certificates of Analysis (COA) confirming 98% purity and Peak X-free status. We also provide full HPTLC testing data and stability reports to your QA and formulation teams.
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